Histamine Definition

Histamine 3D Ball

The Definition of Histamine is a compound that plays a role in regulating physiological function of the stomach and acts as a neurotransmitter. Histamine is also involved in local immune responses. Histamine is produced in basophils and mast cells in response to pathogens. Histamine causes increased capillary permeability of the white blood cells and other proteins. This will help white blood cells fight infection in the tissues. The works intertwined with histamine receptors in the cell. There are 4 types of receptors are known.

1. Histamine Receptor H1

Histamine Receptor H1 found in muscle tissue, the central nervous system, and endothelium. Histamine receptor H1 histamine receptor that is most responsible for the symptoms of allergy. If histamine intertwined with receptor, there will be bronchoconstriction, vasodilation, pain, and itching of the skin

2. Histamine Receptor H2

Histamine Receptor H2 increases gastric acid secretion. Histamine Receptors H2 were identified in the parietal cells

3. Histamine Receptor H3

When active, Histamine Receptor H3 would lead to the release of neurotransmitters, such as norepinephrine histamine, serotonin, acetylcholine.

4. Histamine Receptor H4

Histamine receptor H4 identified mostly in bone marrow cells and basophils. These receptors are also found in the thymus gland, small intestine, large intestine and spleen.

Regulatory function in the body is closely related to histamine. Histamine is released as a neurotransmitter. Inhibitory action of histamine H1 receptor resulted in us sleepy. In addition, histamine also released by mast cells in the genital organs during orgasm.

For people with schizophrenia, the histamine level in the blood is very low. This may occur due to the side effects of antibiotics consumed, causing adverse side effects of histamine, such as quetiapine. However, he will come back better and healthier when his histamine levels back to normal